{"id":15812,"date":"2024-02-15T15:53:41","date_gmt":"2024-02-15T12:53:41","guid":{"rendered":"https:\/\/kanidis.gr\/?page_id=15812"},"modified":"2024-02-15T15:53:41","modified_gmt":"2024-02-15T12:53:41","slug":"immunohistochemistry-in-situ-1","status":"publish","type":"page","link":"https:\/\/kanidis.gr\/en\/immunohistochemistry-in-situ-1\/","title":{"rendered":"Immunohistochemistry > In Situ 1"},"content":{"rendered":"

[vc_row][vc_column width=”1\/6″][vc_column_text]\"ALK[\/vc_column_text][\/vc_column][vc_column width=”4\/6″]

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ALK IQFISH Break-Apart Probe<\/h3><\/div><\/div>[vc_column_text]<\/p>\n
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ALK IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the ALK gene by fluorescence in situ hybridization (FISH). The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.<\/p>\n

Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation breakpoint for a given gene, each labeled with a different fluorochrome. These probes generate signals in normal cells that are closely matched in size and co-localized (two fusion signals). In case of a translocation event, the signals are ‘broken apart’ and no longer co-localize giving e.g. one red, one green and one fusion signal.<\/p>\n<\/div>\n

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ALK IQFISH<\/b><\/a><\/div><\/div>[vc_separator color=”white” css=”.vc_custom_1706609592736{margin-top: 15px !important;margin-bottom: 5px !important;}”][vc_column_text]\u2611 20 Test<\/p>\n

\u2611 IVDR<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator color=”peacoc” css=”.vc_custom_1602852718815{margin-top: 30px !important;margin-bottom: 30px !important;}”][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/6″][vc_column_text]\"ROS1[\/vc_column_text][\/vc_column][vc_column width=”4\/6″]

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ROS1 IQFISH Break-Apart Probe<\/h3><\/div><\/div>[vc_column_text]<\/p>\n
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ROS1 IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the ROS1 gene by fluorescence in situ hybridization (FISH). The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.<\/p>\n

Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation breakpoint for a given gene, each labeled with a different fluorochrome. These probes generate signals in normal cells that are closely matched in size and co-localized (two fusion signals). In case of a translocation event, the signals are ‘broken apart’ and no longer co-localize giving e.g. one red, one green and one fusion signal.<\/p>\n<\/div>\n

[\/vc_column_text][\/vc_column][vc_column width=”1\/6″]

<\/div>
ROS1 IQFISH<\/b><\/a><\/div><\/div>[vc_separator color=”white” css=”.vc_custom_1706609592736{margin-top: 15px !important;margin-bottom: 5px !important;}”][vc_column_text]\u2611 20 Test<\/p>\n

\u2611 IVDR<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator color=”peacoc” css=”.vc_custom_1602852718815{margin-top: 30px !important;margin-bottom: 30px !important;}”][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/6″][vc_column_text]\"RET[\/vc_column_text][\/vc_column][vc_column width=”4\/6″]

<\/div>

RET IQFISH Break-Apart Probe<\/h3><\/div><\/div>[vc_column_text]<\/p>\n
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RET IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the RET gene by fluorescence in situ hybridization (FISH). The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.<\/p>\n

Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation breakpoint for a given gene, each labeled with a different fluorochrome. These probes generate signals in normal cells that are closely matched in size and co-localized (two fusion signals). In case of a translocation event, the signals are ‘broken apart’ and no longer co-localize giving e.g. one red, one green and one fusion signal.<\/p>\n<\/div>\n

[\/vc_column_text][\/vc_column][vc_column width=”1\/6″]

<\/div>
RET IQFISH<\/b><\/a><\/div><\/div>[vc_separator color=”white” css=”.vc_custom_1706609592736{margin-top: 15px !important;margin-bottom: 5px !important;}”][vc_column_text]\u2611 20 Test<\/p>\n

\u2611 IVDR<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator color=”peacoc” css=”.vc_custom_1602852718815{margin-top: 30px !important;margin-bottom: 30px !important;}”][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/6″][vc_column_text]\"MET[\/vc_column_text][\/vc_column][vc_column width=”4\/6″]

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MET IQFISH Probe with CEP7<\/h3><\/div><\/div>[vc_column_text]<\/p>\n
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MET IQFISH Probe with CEP7 (Dako Omnis) is intended for the detection of the MET gene amplification by fluorescence in situ hybridization (FISH). The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.<\/p>\n

In normal diploid cells in metaphase or interphase, the MET IQFISH Probe with CEP7 generates two orange-red signals (MET) and two green signals (chromosome 7). In cells with a gain or amplification of the MET gene or of chromosome 7, the number of signals per cell will be greater.<\/p>\n<\/div>\n

[\/vc_column_text][\/vc_column][vc_column width=”1\/6″]

<\/div>
MET IQFISH<\/b><\/a><\/div><\/div>[vc_separator color=”white” css=”.vc_custom_1706609592736{margin-top: 15px !important;margin-bottom: 5px !important;}”][vc_column_text]\u2611 20 Test<\/p>\n

\u2611 IVDR<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator color=”peacoc” css=”.vc_custom_1602852718815{margin-top: 30px !important;margin-bottom: 30px !important;}”][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column width=”1\/6″][vc_column_text][\/vc_column_text][\/vc_column][vc_column width=”4\/6″][vc_column_text] ALK IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the ALK gene by fluorescence in situ hybridization (FISH). The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens. Break-apart probes consist of two child probes, designed to be on…<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/pages\/15812"}],"collection":[{"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/comments?post=15812"}],"version-history":[{"count":1,"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/pages\/15812\/revisions"}],"predecessor-version":[{"id":15816,"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/pages\/15812\/revisions\/15816"}],"wp:attachment":[{"href":"https:\/\/kanidis.gr\/en\/wp-json\/wp\/v2\/media?parent=15812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}